高 雅
一、个人信息
姓名：高 雅
职称：副教授
专业：原子与分子物理
学历层次：博士研究生
办公室地点：实训楼2208
办公电话：021-67791039
电子邮箱：gaoya@sues.edu.cn
研究方向：计算生物物理；
荧光探针机制与成像理论机制；
计算光学光电材料等；
个人主页：http://faculty.sues.edu.cn/_s3486/main.psp
二、教育经历
2014.06 毕业于华东师范大学原子与分子物理专业获博士学位
三、工作经历
2018.09-2019.09 美国理海大学生命科学系博士后
2017.10-2021.09 华东师范大学化学与分子工程学院博士后
2014.09-至今 上海工程技术大学数理与统计学院讲师，副教授
四、代表性论著 (入职以来一作或通讯)
15. X. Fang, Y. Gao*, C. Wang, H. Chen, T. Zhu*, Exploring the selective mechanism of inhibitors towards different subtypes of class I PI3K, Chem. Phys. Lett.,786, 139174, 2022
14. N. Li, Y. Gao*, F. Qiu*, T. Zhu*, Benchmark Force Fields for the Molecular Dynamic Simulation of G-Quadruplexes, Molecules, 26, 5379, 2021
13. Y. Gao, J. Lee, I. P. S. Smith, H. Lee, S. Kim, Y. Qi, J. B. Klauda, G. Widmalm, S. Khalid, W. Im*, CHARMM-GUI Supports Hydrogen Mass Repartitioning and Different Protonation States of Phosphates in Lipopolysaccharides, J. Chem. Inf. Model., 61, 831, 2021
12. Y. Gao, J. Lee, G. Widmalm*, W. Im*, Modeling and simulation of bacterial outer membranes with lipopolysaccharides and enterobacterial common antigen, J. Phys. Chem. B, 124, 5948, 2020
11. Y. Gao, J. Lee, G. Widmalm*, W. Im*, Preferred conformations of lipooligosaccharides and oligosaccharides of Moraxella catarrhalis, Glycobiology, 30, 86, 2020
10. Y. Zhang, Y. Qu*, J. Wu, Y. Rui, Y. Gao*, Y. Wu*, Naphthalimide end-capping molecular rotors with different donor cores: Tuning emission in wide gamut and cell imaging, Dyes Pigments, 179, 108431, 2020
9. Z. Gao, J. Bao, S. Shi, X. Zhang, Y. Gao*, T. Zhu*, Effect of mutations on drug resistance of smoothened receptor toward inhibitors probed by molecular modeling, Chem. Phys. Lett.,741, 137126, 2020
8. B. Wang, Y. Qi, Y. Gao*, J. Z. H. Zhang*, A method for efficient calculation of thermal stability of proteins upon point mutations, Phys. Chem. Chem. Phys., 22, 8461, 2020
7. Y. Gao, T. Zhu*, J. Z. Chen*, Exploring drug-resistant mechanisms of I84V mutation in HIV-1 protease toward different inhibitors by thermodynamics integration and solvated interaction energy method, Chem. Phys. Lett.,706, 400, 2018
6. Y. Gao, T. Zhu*, C. M. Zhang, J. Z. H. Zhang, Y. Mei*, Comparison of the unfolding and. oligomerization of human prion protein under acidic and neutral environments by molecular dynamics simulations, Chem. Phys. Lett., 706, 594, 2018
5. Y. Gao*, C. M. Zhang, T. Zhu*, A test of AMBER force fields in predicting the secondary structure of alpha-Helical and beta-hairpin peptides, Chem. Phys. Lett., 679, 112, 2017
4. Y. Gao*, C. M. Zhang, J. Z. H. Zhang, Y. Mei*, Evaluation of the coupled two-dimensional main chain torsional potential in modeling intrinsically disordered proteins, J. Chem. Inf. Model., 57, 267, 2017
3. Y. Gao, Y. Mei, J. Z. H. Zhang, Treatment of hydrogen bonds in protein simulations, Advanced Materials for Renewable Hydrogen Production, Storageand Utilization, InTech, ISBN 978-953-51-2219-7, 2015
2. Y. Gao, Y. X. Li, L. R. Mou, B. B. Lin, J. Z. H. Zhang, Y. Mei, Correct folding of an alpha-helix and a beta-hairpin using a polarized 2D torsional potential, Sci. Rep.,5, 10359, 2015
1. Y. Gao, Y. X. Li, L. R. Mou, J. Z. H. Zhang, Y. Mei, Coupled two-dimensional main-chain torsional potential for protein dynamics II: performance and validation, J. Phys. Chem. B, 119, 4188, 2015
五、代表性科研项目
1. 国家自然科学基金青年项目, 21503132, 主持.
2. 中国博士后科学基金面上资助，2018M632058, 主持.
3. 上海市人才计划“晨光计划”, 15CG59, 主持.
4. 上海工程技术大学人才计划“展翅计划”, 主持.
六、主要荣誉奖励
2017 上海工程技术大学优秀教育工作者
七、主要学术组织社会兼职
Chemical Biology & Drug Design, Chinese Journal of Chemical Physics, Current Alzheimer Research等期刊审稿人
